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硕士生导师

安贵鹏

副主任医师
硕导
个人简介 学术论文 科研项目 学会任职

医学博士,副主任医师,硕士研究生导师,宾夕法尼亚大学访问学者。

主要研究方向:动脉粥样硬化的免疫机制和冠心病的临床研究。

长期从事心内科临床一线工作,对高血压病、冠心病、心力衰竭等心血管疾病的诊治积累了丰富的临床经验,专注于复杂冠脉病变和心脏瓣膜病变的介入治疗。兼任卫健委冠心病介入诊疗培训基地导师、山东省青年联合会第十三届委员会委员。2015年度齐鲁医院优秀教师,2017年度民盟山东省委先进个人,2017和2018年先后两次当选为中国医师协会冠脉介入专业委员会优秀青年介入医师。

1.Song H, Bao W, Wang H, An G, Feng J, Wang R, Zhang Y, An F. Effects of extended-release felodipine on endothelial vasoactive substances in patients with essential hypertension. Clin Chem Lab Med. 2008,46:393-395.

2.An G, Miwa T, Song WL, Lawson JA, Rader DJ, Zhang Y, Song WC. CD59 but not DAF deficiency accelerates atherosclerosis in female ApoE knockout mice. Mol Immunol. 2009,46:1702-1709.

3.Dong Z, An F, Wu T, Zhang C, Zhang M, Zhang Y, An G*, An F. PTX3, a key component of innate immunity, is induced by SAA via FPRL1-mediated signaling in HAECs. J Cell Biochem. 2011,112:2097-2105. (*Co-corresponding author)

4.Meng X, Zhang K, Li J, Dong M, Yang J, An G, Qin W, Gao F, Zhang C, Zhang Y. Statins induce the accumulation of regulatory T cells in atherosclerotic plaque. Mol Med. 2012,18:598-605.

5.Meng X, Li W, Yang J, Zhang K, Qin W, An G, Gao F, Wang Y, Zhang C, Zhang Y. Regulatory T cells prevent plaque disruption in apolipoprotein E-knockout mice. Int J Cardiol. 2013 ,168:2684-2692.

6.Guo T, Wang J, Yang J, Chen W, An G, Fan L, Peng Q. Lentivirus-mediated RNA interference of chymase increases the plaque stability in atherosclerosis in vivo. Exp Mol Pathol. 2013,95:51-56.

7.Lou Y, Liu S, Zhang C, Zhang G, Li J, Ni M, An G, Dong M, Liu X, Zhu F, Zhang W, Gao F, Chen YH, Zhang Y. Enhanced atherosclerosis in TIPE2-deficient mice is associated with increased macrophage responses to oxidized low-density lipoprotein. J Immunol. 2013,191:4849-4857

8.An G, Du Z, Meng X, Guo T, Shang R, Li J, An F, Li W, Zhang C. Association between low serum magnesium level and major adverse cardiac events in patients treated with drug-eluting stents for acute myocardial infarction. PLoS One. 2014,9:e98971.

9.An G, Du Z, Meng X, Guo T, Li G, Chen Y, Li J, An F, Zhang Y, Li W, Zhang C. Risk factors for long-term outcome of drug-eluting stenting in adults with early-onset coronary artery disease. Int J Med Sci. 2014,11:721-725.

10.Meng X, Yang J, Zhang K, An G, Kong J, Jiang F, Zhang Y, Zhang C. Regulatory T cells prevent angiotensin II-induced abdominal aortic aneurysm in apolipoprotein E knockout mice. Hypertension. 2014,64:875-882.

11.An G, Ren G, An F, Zhang C. Role of C5a-C5aR axis in the development of atherosclerosis. Sci China Life Sci. 2014 ,57:790-794.

12.An G, Li B, Liu X, Zhang M, Gao F, Zhao Y, An F, Zhang Y, Zhang C. Overexpression of complement component C5a accelerates the development of atherosclerosis in ApoE-knockout mice. Oncotarget. 2016 ;7:56060-56070

13.Meng X, Zhang K, Kong J, Xu L, An G, Qin W, Li J, Zhang Y. Deletion of resistin-like molecule-beta attenuates angiotensin II-induced abdominal aortic aneurysm. Oncotarget. 2017;61:104171-104181

14.Liu B, Kong J, An G, Zhang K, Qin W, Meng X. Regulatory T cells protected against abdominal aortic aneurysm by suppression of the COX-2 expression. J Cell Mol Med. 2019 ;10:6766-6774.

15.Cheng Z, Hu M, Tao J, Yang H, Yan P, An G*, Wang H.The protective effects of Chinese yam polysaccharide against obesity-induced insulin resistance. J Funct Foods.2019;55: 238-247 (*Co-corresponding author)

1. C5a促动脉粥样硬化及其机制的实验研究。国家自然科学基金(No. 81000125),1/2011-12/2013,项目负责人。

2. 补体在心肌炎发病过程中的作用及其致病机制的实验研究。教育部博士点基金(No. 20100131120057),1/2011-12/2013,项目负责人。

3. 补体系统促动脉血栓形成的机制研究。山东省优秀青年科学家科研奖励基金(No. BS2012YY017),1/2013-12/2015,项目负责人。

4. C3a受体促动脉粥样硬化的机制研究。山东省自然科学基金(ZR2016HM0),1/2017-12/2019,项目负责人。

中国医师协会心脏重症专家委员会青年委员

中国医疗保健国际交流促进会胸痛分会委员

中华中医药学会介入心脏病学分会委员

山东省医师协会心力衰竭专业委员会青委会副主任委员

山东省医师协会心血管介入医师分会委员

山东省医师协会心内科医师分会委员

山东省医师协会胸痛专业委员会委员

山东省医师协会高血压分会青年委员